Novel Strategies to Test Biological Hypotheses in Early Drug Development for Advanced Prostate Cancer

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Novel strategies to test biological hypotheses in early drug development for advanced prostate cancer.

BACKGROUND Major advances in our understanding of the underlying biology of prostate cancer have helped to herald a new era in the treatment of castration-resistant prostate cancer (CRPC), with 5 new agents having shown a survival advantage in the last 3 years and an impressive number of promising novel agents now entering the clinic. CONTENT We discuss the challenges facing drug development ...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 2013

ISSN: 0009-9147,1530-8561

DOI: 10.1373/clinchem.2012.185157